Category Archives: IPTp

Improving intermittent preventive treatment for pregnant women (IPTp) coverage in 5 districts in Chad and Cameroon

Kodjo Morgah and Naibei Mbaïbardoum of Jhpiego with support from the ExxonMobil Foundation ave been working to increase interventions that protect pregnant women from malaria. The results below were shared at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene.

Malaria is the leading cause of morbidity and mortality in Cameroon and Chad, where an estimated 500,000 and 1.5 million cases occur every year, respectively. In Cameroon, 55% of hospitalizations and 241 deaths among pregnant women reported in 2010 were due to malaria. In Chad, malaria accounted for 30% of hospital admissions and 41% of deaths among pregnant women in 2013.

To improve uptake of intermittent preventive treatment for pregnant women (IPTp) for malaria in 5 districts in Chad and the Kribi district of Cameroon, Jhpiego adopted strategies targeting the 4 levels of the health system in each country: updating national policies and guidelines, building capacity of providers, building community health workers’ (CHWs) capacity, and engaging in behavior change communication.

Nationally, Jhpiego provided technical guidance to the Ministries of Health to develop tools including: training and malaria in pregnancy (MIP) reference manuals for providers and CHWs, guidelines on IPTp, and key supervision and data collection tools. At the regional/district levels, 38 supervisors were trained, and they conducted 248 supervisory visits in both countries, reaching 137 health facilities.

At the facility level, 234 providers were trained in malaria prevention and management, MIP, data collection and commodity management. At the community level, 146 CHWs in both countries were trained to raise awareness on malaria prevention and control.

In Chad, CHWs referred 6424 pregnant women for antenatal care/IPTp and 11679 pregnant women for malaria treatment in 2014 and 2015. Health facility and CHW data collection tools were revised and monthly validation of district data was implemented to improve data reliability, completeness, and readiness.

As a result of Jhpiego’s activities in Kribi, IPTp rates increased from the start of the project in 2012 to 2015: from 70% to 83% (IPTp1), 61% to 80% (IPTp2), and 12.7% to 28.1% (IPTp3). Similarly, from 2012 to 2015 in Chad, IPTp1 rates increased from 40% to 83% and from 30% to 50% for IPTp2. These gains are a result of training paired with coaching and supervision activities of trained providers and targeted facilities.

 

Results of an evaluation of the Toolkit to Improve Early and Sustained Intermittent Preventive Treatment in Pregnancy (IPTp) Uptake in Mozambique and Madagascar

Lalanirina Ravony, Elana Fiekowsky, Lisa Noguchi, Patricia P. Gomez, Jean Pierre Rakotovao, Eliane Razafimandimby, Armindo Tiago, Kathryn Smock, Arsene Ratsimbarisoa, Kristen Vibbert, and Robert Sellke shared their efforts to apply a toolkit to enable health providers to ensure better uptake of intermittent preventive treatment for malaria during antenatal clinics. As seen below, they presented their findings at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene.

Malaria in pregnancy (MIP) is a leading cause of maternal and newborn morbidity and mortality; however uptake of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP), an effective prevention tool, remains alarmingly low across sub-Saharan Africa, including Mozambique and Madagascar.

The WHO 2012 policy recommendations to prevent MIP include early enrollment into antenatal care (ANC), accurate estimation of gestational age (GA) and administration of IPTp-SP during ANC visits beginning early in the second trimester, spaced at least one month apart. Preventing MIP remains a challenge in settings with inconsistent application of these recommendations and inadequate provider training in estimating GA.

To improve adherence to these recommendations, a toolkit was designed which includes a job aid with an algorithm to guide providers during ANC visits to determine IPTp-SP eligibility. Twenty-four providers from 24 facilities in Madagascar and 29 providers from seven facilities in Mozambique were trained on use of the job aid and interviewed three months later about their experience.

Individual providers were interviewed using a questionnaire to assess the clarity and utility to the job aid, and their opinions of the practicality of the orientation. Interviewers also gathered information on years of experience and clinical certification. All providers reported that the job aid reminded them to estimate GA and measure fundal height, which is particularly helpful since few women remember the date of their last menstrual period (LMP).

Health workers also reported that the job helped them encourage the use of long-lasted insecticide treated nets, and reminded them of the proper timing to start IPTp-SP. We conclude that the toolkit is useful to prompt providers to calculate GA and offer IPTp as early as possible in the second trimester.

Future potential directions include revision of all Toolkit components to reflect input from this evaluation, including development of a wall poster version to enhance readability, and inclusion of a pregnancy wheel to facilitate calculation of GA and estimated date of delivery.

This poster was made possible by the generous support of the American people through the United States Agency for International Development (USAID), under the terms of the Cooperative Agreement AID-OAA-A-14-00028. The contents are the responsibility of the Maternal and Child Survival Program and do not necessarily reflect the views of USAID or the United States Government.

Results from a Formative Evaluation of the Malaria in Pregnancy Case Management Job Aid in Nigeria

Job Aids can provide valuable assistance to health workers, but it is important to evaluate if they serve the intended purpose.  With support from USAID’s Maternal and Child Survival Program, Bright Orji, Enobong Ndekhedehe, Elana Fiekowsky, Patricia Gomez, Aimee Dickerson, Reena Sethi, Bibian Udeh, Kristin Vibbert, and Robert Sellke reported at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene on their evaluation of a Job Aid for Nigeria on the prevention of malaria in pregnancy as seen below.

Annually, nearly 7 million pregnant women in Nigeria are at risk of malaria in pregnancy (MIP). Although antenatal care is the platform for the prevention and treatment of MIP, malaria is also treated at outpatient departments.

It is known that women of reproductive age (WRA) are often treated for malaria without assessing pregnancy status, although artemisinin combination therapies are contraindicated in the first trimester of pregnancy, and many pregnant women do not receive the recommended low cost interventions.

In order to increase access to these MIP interventions, the President’s Malaria Initiative supported the Maternal and Child Survival Program and partners to develop a two-page job aid for case management of uncomplicated malaria among WRA. In collaboration with the Nigeria Malaria Elimination Program, the job aid was evaluated in Ebonyi State, a high malaria burden area, to determine providers’ perceptions of its clarity, acceptability, and utility.

A half-day workshop on use of the job aid was provided to 35 health workers (nurses – 20%; nurse-midwives – 20%; community health extension workers – 48%; and medical doctors – 12%) already trained on MIP case management, selected from 15 facilities where WRA seek care. After 3 months of use, a one-page questionnaire was administered to 34 health workers.

One-hundred percent stated that the job aid helped them to do the following: identify pregnant women among the WCBA presenting with fever; use rapid diagnostic tests to diagnose malaria; and treat uncomplicated MIP. Sixty-eight percent used the job aid to provide correct treatment for severe malaria and 88% used it while providing services all or most of the time.

The results indicated that after a half-day orientation on use of the job aid, health workers were able to use it to help them identify women who may be pregnant and provide appropriate treatment for uncomplicated MIP. They are also able to explain its use to colleagues.

It is suggested that a poster-size version could be printed and disseminated to appropriate cadres of health workers in clinics where WRA seek care for fever, as it is anticipated that providers could benefit from its use.

This poster was made possible by the generous support of the American people through the United States Agency for International Development (USAID), under the terms of the Cooperative Agreement AID-OAA-A-14-00028. The contents are the responsibility of the Maternal and Child Survival Program and do not necessarily reflect the views of USAID or the United States Government.

Contribution of the Standards-Based Management and Recognition (SBM-R) approach to fighting malaria in Burkina Faso

Quality improvement tools play an important role in ensuring better malaria services.  Moumouni Bonkoungou, Ousmane Badolo, and Thierry Ouedraogo describe how

Standards Based Management and Recognition Approach to Quality Improvement

Jhpiego’s quality approach, Standards-Based Management and Recognition, was applied to enhancing the provision of malaria services in Burkina Faso at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene. Their work was supported through the President’s Malaria Initiative and the USAID Improving Malaria Care Project.

In 2015, Burkina Faso recorded 8,286,463 malaria cases, including 450,024 severe cases with 5379 deaths. The main reasons for these death are:  Inadequate application of national malaria diagnosis and treatment guidelines, delays in seeking health care and poor quality of case management.

The Standards-Based Management and Recognition (SBM-R) approach is used to improve quality of care using performance standards based on national guidelines. SBM-R includes the following steps:

  • set performance standards
  • implement the standards
  • monitor progress and
  • recognize as well as celebrate achievements

Areas or domains assessed by the approach are: services organization, case management at both health center and community, Intermittent Preventive Treatment in Pregnancy (IPTp), promotion of Long Lasting Insecticide treated Nets (LLIN) use and infection prevention and control.

Since June 2016, 26 health facilities in three regions have been implementing SBMR. Therefore, 105 health workers have been trained. Performance progress was measured through 5 evaluations including baseline. Baseline has shown the highest score was 47% (Kounda) while the lowest was 9% (Niangoloko).

The main issues observed were: lack of program activities, management tools, handwashing facilities, LLINs and misuse of Rapid Diagnosis Tests. Their cause was determined and an improvement plan was developed by each site. The second, third and final evaluations revealed a change in performance scores for all sites.

The external evaluation showed 17 out of 26 health facilities with a score higher than 60%; among them 10 with a score above 80% (Bougoula, 94%). At the same time, IPTp 3 increased from 34.48% in 2014 to 78.38% in 2016 and no malaria death has been registered since October 2015.

For the site under 80% the key reasons were: staff turnover, commodities stock-out and lack of infrastructure. The process continues with recognition of health facilities and supporting others (those at less than 80%) to reach the desired performance level. The SBM-R approach appears to be a great tool for improving quality and performance of health facilities.

Missed Opportunities for Uptake of Intermittent Preventative Treatment for Malaria in Pregnancy in Tanzania

A major reason that coverage targets for intermittent treatment of malaria in pregnancy fall short are missed opportunities at health service sites. Jasmine Chadewa, Yusuph Kulindwa, Dunstan Bishanga, Mary Drake, Jeremie Zoungrana, Elaine Roman, Hussein Kidanto, Naomi Kaspar, Kristen Vibbert, and Lauren Borsa share what they have learned about this issue at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene.

About 35 million people in Tanzania are at risk of malaria, with pregnant women and under five children being the most vulnerable. The Tanzania National Malaria Control Program’s (NMCP) Strategic Plan for 2007–2012 reports that malaria accounts for 30% of the national disease burden, with about 1.7 million cases per year among pregnant women.

To prevent the effect of malaria in pregnancy, the Tanzania Government adopted IPTp3+ therapy for pregnant women per the WHO recommendations for IPTp-SP. This study explores missed opportunities to deliver IPT by looking at predictors causing the drop between coverage of IPTp2 (34%) and IPTp3+ (7%).

The study examined Tanzania Demographic and Health Survey (TDHS) 2015/2016 data on women aged 15-49 with a live birth in the two years preceding the survey and at least 2 doses or more of IPTp during ANC (n=4219) to identify factors associated with differences in IPTp uptake. Variables of interest were identified, recoded and generated as required. Data was analyzed using STATA v14, whereby frequency distributions were calculated and cross-tabs and logistic regressions were done comparing dependent and independent variables.

The analysis shows the factors contributing to the drop of IPTp uptake include wealth (the richest people are 2.5 times more likely to take at least three doses of IPTp) and education (those with no education are less likely to take more doses of IPTp compared to those who are educated). Residency is the largest contributing factor: 50% of pregnant mothers in rural areas are less likely to take three or more doses of SP.

Clients living within 5 km of health facilities have higher uptake of IPTp3+ compared to their counterparts who live further from the health facilities (33% less likely). However, our analysis shows that there is no correlation between IPTp3+ uptake and number of ANC visits, health insurance or number of children.

Based on these results, it is important to strategize to make health services and education more accessible to the population in order to increase IPTp uptake among pregnant women.

Baseline for Coverage of Intermittent Preventive Treatment of Malaria in Pregnancy for Planning Community Interventions in Burkina Faso

Under supervision from health center Community Health Worker provides SP for IPTp to Pregnant Woman

Now that the World Health Organization recommends that pregnant women in high and stable malaria transmission areas receive three or more doses of Intermittent Preventive Treatment (IPTp) with Sulfadoxine-pyrimethamine, it is necessary to learn ways to reach more women with this intervention. William R. Brieger, Mathurin Dodo, Danielle Burke, Ousmane Badolo, Justin Tiendrebeogo, Kristen Vibbert, Susan J Youll, and Julie R Gutman conducted a baseline household survey of recently pregnant women in Burkina Faso to learn about the extent of current IPTp coverage and where improvements are needed. With support from the US President’s Malaria Initiative and the USAID Maternal and Child Survival Program Their findings were made available at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene.

The World Health Organization recommends intermittent preventive treatment (IPTp) to prevent the adverse effects of malaria in pregnancy in high burden settings; IPTp coverage has lagged behind international targets. In Burkina Faso, the 2014 Malaria Indicator Survey found that 22% of women received 3 or more doses of IPTp (IPTp3). In 2014, Burkina Faso’s IPTp policy was updated from recommending 2 doses to providing at least 3 doses of IPTp. Prior studies have suggested that use of community health workers to deliver IPTp can increase coverage.

To improve IPTp coverage, we will pilot community delivery of IPTp within 3 southern districts: Po, Ouargaye, and Batie. Here we report results from a baseline assessment in the selected districts. Health Management Information System (HMIS) data for 2015 were collected in each district, and IPTp3 coverage was 37%. Four health facilities per district were randomly selected to participate in the pilot. In 2017, a baseline household survey was conducted among recently pregnant women in the catchment areas of these health facilities.

Women were asked to recall the number of antenatal care (ANC) visits and IPTp doses they had received during their most recent pregnancy. The same information was extracted from their ANC cards. A total of 374 women were interviewed during the baseline survey.

ANC attendance was reported to be 98% for any visit, and 84% for four visits; these rates were 90% and 62% as documented on the ANC cards. Over 95% of women recalled receiving the first dose of IPTp, while over 80% of cards verified that the first dose was given.

Receipt of the third IPTp dose was 62% by recall and 52% as recorded on the ANC cards, while receipt of 4 doses was 32% by recall and 19% per the ANC cards. IPTp3 coverage was not associated with parity or educational level.

Following implementation of the revised IPTp policy, there has been a substantial improvement in IPTp coverage, though more work is needed to achieve the national 85% coverage target.

Our pilot will examine the impact that delivery of IPTp by community workers has on IPTp coverage, with endline surveys planned for 2018.

Potential Contribution of Community-Based Health Workers to Improving Prevention of Malaria in Pregnancy

Justin Tiendrebeogo, Ousmane Badolo, Mathurin Dodo, Danielle Burke, and Bill Brieger of Jhpiego have designed and are implementing a study to determine the effect of delivering Intermittent Preventive Treatment for Malaria in Pregnancy through community health workers in Burkina Faso with the support of the US President’s Malaria Initiative and the USAID Maternal and Child Survival Project. They have shared the design and start-up activities for the study at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene. A summary follows:

CHW Flipchart Page

The Ministry of Health of Burkina Faso with the support of its partners initiated a study on the feasibility of increasing provision of Intermittent Preventive Malaria Treatment in pregnant women (IPTp) with sulfadoxine-pyrimethamine (SP) by involving existing community-based health workers (CBHWs). As Burkina Faso adopted the WHO recommendations for more doses of IPTp during pregnancy, it was proposed that the challenge of achieving coverage of third, fourth and additional doses could be met using CBHWs.

The approved protocol calls for CBHWs to refer pregnant women to antenatal care (ANC) to receive their first IPTp dose. Subsequent doses at one-month intervals would be provided by trained CBHWs, who would report back to supervising midwives at the ANC clinics. Several steps were taken to gain approval and set up the intervention.

CHW Using Flipchart

First, IPTp data from the health information system was gathered. IPTp coverage based on ANC registration in the 6 intervention clinics was 69% IPTp1, 68% IPTp2, 56% IPTP3, and 1% IPTp4. Similar information was obtained from the 6 control clinic catchment areas. Situation analysis found that while CBHW curriculum stresses the importance of ANC, it does not address IPTp at community level.

In response updated training materials have been developed. The study team also collected information on village size and availability of CBHWs, especially females. Among the villages in the catchment of the 6 intervention ANC clinics, 33 were found to lack female CBHWs.

Supervisory Meeting

As a result, the team needed to recruit additional female CBHWs, as revised national recruitment guidance stressed attainment of primary school certificate over gender, meaning mainly men had been hired previously. Two institutional review boards were involved and suggested the need to address the potential rare side effects of SP and concerns that community IPTp would not detract from ANC clinic attendance.

Since district and clinic level health staff will be involved in implementing the program using the national CBHW program, lessons learned from this effort to expand the work of CBHWs in preventing malaria in pregnancy should be applicable and adaptable to the whole country.

Using rapid task analysis to strengthen Pre-Service Education (PSE) learning and performance of critical malaria interventions in Liberia

Understanding the tasks that health workers perform in real life can improve their basic Training. Marion Subah of MCSP and Jhpiego shares experiences in using Task Analysis to improve pre-service training of midwives and lab technicians in Liberia. Her findings summarized below, are presented at the American Society of Tropical Medicine’s 66th Annual Meeting.

Health worker task analysis helps human resource planners and managers update pre-service education (PSE) curricula and plan needed in-service training. In Liberia, a task analysis was conducted focusing on Liberia’s midwives’ and Medical Laboratory Technicians’ (MLT) work practices.

Task lists were developed using curricula, job descriptions and professional scope of practice, and validated by key stakeholders for each cadre. Responses from 25 MLTs and 26 midwives were examined that addressed the following questions:

  1. How often do you do the task (frequency)?
  2. Where did you learn to do the task (location)?
  3. How well do you think you are able to perform the task (performance)?
  4. How critical is the task in terms of patient and/or public health outcomes (criticality).

Eligibility criteria included those currently practicing between 6 months and 5.5 years following graduation. Midwives were assessed for five tasks relating to malaria service provision, including provision of preventive treatment for malaria in pregnancy, management of vector borne diseases, diagnosis and management uncomplicated malaria in adults and children (respectively), and provision of malaria preventive services.

Lab technicians were assessed for one malaria task, performance of parasitological tests. On average 61% of midwives learned these malaria tasks in PSE, 74% said they performed these tasks daily, 80% felt proficient in performing the tasks, and 82% rated the tasks moderate to high in criticality. For MLTs, 88% learned malaria testing in pre-service education, 100 % performed this task daily, 77% felt they were proficient and 93% said the task was of moderate to high criticality.

Task Analysis Flow Chart

The results from this rapid task analysis are being applied to the current curricula review. Courses that could be updated or strengthened have been identified. Malaria Case Management Technical Update and Effective Teaching Skills Training are being organized for tutors at the training schools. Finally, integrated supportive supervision tools are being strengthened to improve performance of these malaria tasks by midwives and lab technicians.

Implementation of a Quality Improvement Approach for Malaria Service Delivery in Zambezia Province, Mozambique

Baltazar Candrinho, Armindo Tiago, Custodio Cruz, Mercino Ombe, Katherine Wolf, Maria da Luz Vaz, Connie Lee and Rosalia Mutemba are sharing their work during a scientific session on enhancing quality of care for malaria services in Mozambique at the 66th Annual Meeting of the American Society of Tropical Medicine 66th Annual Meeting on 6 November 2017. A summary of their talk follows:

In Mozambique, malaria in pregnancy (MIP) is one of the leading causes of maternal and newborn morbidity and mortality. Malaria also accounts for over 40% of deaths in children less than five years old. With provincial and facility-level commitment, a simple and comprehensive quality improvement (QI) system has been established in 10 of 16 districts in Zambezia Province.

Since 2016, the Mozambique Ministry of Health (MOH) and Zambezia Provincial Health Directorate, in collaboration with partners, have implemented a malaria QI effort based on the Standards-Based Management and Recognition (SBM-R) approach. A standards-based approach to improving quality of malaria care engages both management and service providers to work together to assess the current performance, address gaps to ensure that all patients receive a minimum (standardized / evidence-based) package of care, and ultimately improve patient outcomes and facility performance.

Thirty-one performance standards in five content areas (MIP, Case Management, Laboratory, Pharmacy, and Management of Human Resources and Malaria Commodities) were developed and adopted by the MOH in 2016. With support from partners, 40 health workers, including managers, clinicians and lab technicians, received training on SBM-R, and facility QI teams were established.

These teams use checklists based on standards to conduct quarterly assessments that identify performance gaps, and then develop action plans to address areas of improvement. The MOH antenatal care and child health registers also contain information on coverage of key malaria interventions, including IPTp, and malaria diagnosis and treatment during pregnancy and for children under five with fever.

Average attainment of standards at baseline in 20 health facilities was 30%, and is expected to improve as implementation progresses with quarterly application of the checklist (data will be available before November). Improvements in key malaria indicators for pregnant women and children under five years old are expected as the percentage of standards attained increases.

Improving Early ANC Attendance and IPT Uptake through Community Health Volunteers

Community health workers are playing an increasing role in maternal health programming.  Augustine Ngindu, Susan Ontiri, Gathari Ndirangu, Beth Barasa, Evans Nyapada, David Omoit, Johnstone Akatu, and Mildred Mudany of The Matewrnal and Child Survival Program, The Kenya Ministry of Health and Jhpiego share their experiences in Kenya at the 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene in Baltimore on 2017-11-06.  If you are in Baltimore, hear more at Scientific Session 13. Below is an abstract of their presentation

Kenya adopted the use of intermittent preventive treatment with sulfadoxine pyrimethamine in 1998 but the proportion of pregnant women receiving at least two doses (22% (2010) and 56% (2015) has remained below the national target of 80%. In 2015, the country adopted an IPTp3 indicator for monitoring IPTp uptake; that year, the proportion of women taking at least 3 doses was 38% (2015).

Some of the factors leading to low IPTp coverage include poor knowledge on the need for early antenatal care (ANC), distances to health facilities, sociocultural practices and a lack of financial resources. In 2012, community health volunteers (CHVs) were enlisted through a pilot program in one county to deliver messages aimed at increasing the proportion of women starting ANC ? 20 weeks of gestation and thus expand the proportion of women receiving IPTp early in the second trimester.

A community survey in 2013 showed an increase in IPTp2 from 22% in 2010 to 63%. The practice was considered a success story, and was subsequently replicated in 30 sub-counties, in 4 out of 14 malaria endemic counties. The rollout involved training of 9,042 CHVs, in 761 community units. Between 2015 and 2016, the CHVs reached 86,433 women with MiP messages. During this time, there was an average increase in IPTp1 from 51% to 68%, and IPTp2 increased from 42% to 55% (p? 0.001). This could be attributed to early ANC attendance, which increased from 32% to 48% in the same period.

The use of CHVs to sensitize pregnant women to start IPTp early in the second trimester and continue with scheduled ANC visits increases the probability that women will receive the recommended IPTp-SP doses. The rollout of the practice to other malaria endemic counties is likely to have contributed to increase in IPTp uptake in the four target counties.

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